Mitral leaflet enlargement prevents functional Mitral Regurgitation in Aortic Regurgitation patients.

Left ventricle dilatation is common in patients with aortic regurgitation but incidence of functional mitral regurgitation is less common. This has been hypothiesed secondary to compensatory increase in mitral leaflet area which prevents functional mitral regurgitation in compensated aortic regurgitation.

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Low gradient preserved ejection fraction severe aortic stenosis (Paradoxic aortic stenosis)

We all know low gradient reduced ejection fraction severe aortic stenosis, it evaluation and management. But occurrence of low gradient severe aortic stenosis with preserved ejection fraction is controversial and most of often it is concluded as echo error.Classically Severe

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Is Self management of INR for warfarin, better than dabigatran?

Dabigatran is indicated in non valvular AF and not advised in mechanical valves and valvular AF, this is one of the major limitations of dabigatran. In developing countries mitral stenosis is still one of the commonest causes of AF so

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Prosthetic valve thrombosis: TROIA Trial. Is low dose and slow t-PA better than surgery

Guidelines for treatment of prosthetic valve thrombosis (PVT) are different by each organization. This is largely because there are no randomized clinical trials; most of guidelines are formed by expert opinion. Surgery is recommended as first line therapy by European

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Correlation of Opening snap loudness with first heart sound intensity in mitral stenosis

Intensity of first sound and opening snap loudness are directly propositional in isolated mitral stenosis, i.e. if first sound is loud, opening snap will also be loud, and if first heart sound is decreased in intensity than opening snap will

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Lipoprotein a (Lp(a)) genetic variant doubles the causal risk of Aortic valvular calcification.

In the last 15 to 20 years our understanding of aortic valve calcification has changed from just simple degenerative disease to disease secondary to an active process involving endothelial dysfunction, lipid accumulation, an inflammatory infiltrate. With this understanding many potential

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