Impact of ATP4 guidelines on non statin drugs in lipid management

ATP4 which is published in Nov 2013 came up with huge change in lipid guidelines. ATP 4 has focused on atherosclerotic events i.e. MI and stroke rather than surrogates like LDL HDL Triglycerides values. 
Lipid level treatment and atherosclerosis events
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Atrial fibrillation treatment made easy by neurologists

Recent guidelines by American Association of Nuerology  published in their official journal  Neurology  have made treatment of atrial fibrillation to prevent stroke easy, they have made guideline for developing countries too, and these guideline do take account bleeding … Read the rest

Perioperative beta blockers to give or not give.

Recent European in 2009 and American guidelines advise to use  beta blockers in patients undergoing non cardiac surgery for preventing vascular events.  These guidelines were predominantly based on DECREASE trials. 2 years back fabrication of DECREASE trials data was detected

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Mediterranean diet and olive oil in Indian context

Recently PREDIMED trial  has shown advantages of Mediterranean diet (MD) in Spanish population. Traditional MD is rich in fruits, vegetables and legumes.  It has moderate intake of fish, dairy products, and wine and small amount of meat, poultry and sweets.

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Game behind, premature termination of Random Control trials for extraordinary benefits.

These days increasing number of clinical trials (RCT) are terminated prematurely for claim of extraordinary benefit of experimental drug, procedure or investigation. Such prematurely terminated trials usually are published in high impact journal and get immediate recognation and acceptance of
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How to prevent law suits against doctors when doctor is at fault.

Today I was reading an article from heart-wire “Patients Who Won’t Sue Their Doctors — Even When They Could” I found it interesting; I thought I should share my views on this. All of us know, we humans can make

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Do all older people need statin as per new Atherosclerotic risk calculator?

All ready there is lot of critics around new atherosclerotic risk calculator launched by ACC/AHA in Nov 2013 along with ATP 4 cholesterol guide lines.  It is said to overestimate the 10 year risk of Atherosclerotic cardiac and stroke risk. … Read the rest

Drug price control of statin may not useful as per new guidelines

There is a paradigm shift in treatment of patient for prevention of atherosclerotic disease and management of cholesterol as per new guide lines i.e. ATP 4 2013. In these new guidelines there are no targets to which cholesterol need to
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