Why treating stage 1 hypertension has no benefit?

It is very puzzling for most of us why stage1 hypertension has not shown reduction of CV events.  Stage 1 hypertension is 140-159/ 90-99 mmHg.
The results from Lewington et al meta-analysis, have shown that the cardiovascular mortality doubles from
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Spironolactone in resistant hypertension, after simplicity HTN three

Resistant hypertension is defined as persistent increased blood pressure above the level of set targets for example 140/90 even with three drugs in optimum doses, of them one has to diuretic. Even if four drugs are used and BP is

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Should cardiologist stay away from DPP-4 inhibitors in patients with heart failure?

Few days’ back I read article about cardiac benefits of incretin based therapy. How these new classes of drugs reduce the infarct size following MI , PCI and etc. however in that article too GLP 1 agonist did better job … Read the rest

Do all older people need statin as per new Atherosclerotic risk calculator?

All ready there is lot of critics around new atherosclerotic risk calculator launched by ACC/AHA in Nov 2013 along with ATP 4 cholesterol guide lines.  It is said to overestimate the 10 year risk of Atherosclerotic cardiac and stroke risk. … Read the rest

Drug price control of statin may not useful as per new guidelines

There is a paradigm shift in treatment of patient for prevention of atherosclerotic disease and management of cholesterol as per new guide lines i.e. ATP 4 2013. In these new guidelines there are no targets to which cholesterol need to
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Non-cardiac surgery following stenting and perioperative discontinuation of antiplatelet drugs

During perioperative phase surgeons are afraid of bleeding risk due antiplatelet drugs on the other hand temporary cessation of antiplatelet drugs during this phase my increase the chance of stent thrombosis is concern of cardiologist. This lead to consensus with … Read the rest